Anathbandhu  Chaudhuri

Assistant Professor


Education

Ph.D.: Animal Physiology, University of Calcutta, India, 1988

Postdoctoral research: University Alabama and University of Nebraska Medical Center

Research Interests

  • Herbicide induced neurological disorders using fruit fly (Drosophila melanogaster) as a model system.
  • Modeling the progression of colon cancer and metastasis in mouse models.

Selected Publications

  1. Bednářová, A., Hanna, M.E., Durham, I., England, A., Chaudhuri, A., Krishnan, N. (2017) Lost in translation: Defects in tRNA modifications and neurological disorders. Mol. Neurosci. 10(135) DOI: 10.3389/fnmol.2017.00135.
  2. Agarwal, E., Chaudhuri, A., Leiphrakpam, P.D., Haferbier, K.L.,  Brattain, M.G., Chowdhury, S. (2014)  Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer , BMC Cancer , 14:14514:145. doi: 10.1186/1471-2407-14-145.
  3. Geng, L , Chaudhuri, A., Talmon, G., Wisecarver, J., Are, C., Brattain, M., Wang, J. (2014) MicroRNA-192 suppresses liver metastasis of colon cancer. Oncogene 33(46):5332-40. doi: 10.1038/onc.2013.478.
  4. Geng, L., Chaudhuri, A., Talmon, G., Wisecarver, J.L., Wang, J. (2013) TGF-beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis, PLoS One, 8(3):e59918. doi: 10.1371/journal.pone.0059918.
  5. Inamdar, A.A., Chaudhuri, A., O’Donnell, J.M. (2012)The protective effect of minocycline in a paraquat-induced Parkinson’s disease model in Drosophila is modified in altered genetic backgrounds. Parkinson’s Disease. 2012:938528. doi: 10.1155/2012/938528.
  6. Liu, X-Q., Rajput, A., Geng, L., Ongchin, M., Chaudhuri, A., Wang, J. (2011) Restoration of TGFβ type II receptor expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo. Biol. Chem, 286(18):16082-90. doi: 10.1074/jbc.M111.221697.
  7. Del Debbio, C.B., Balasubramanian, S., Parameswaran, S., Chaudhuri, A., Qiu, F., Ahmad, I. (2010) Notch and Wnt signaling mediated rod photoreceptor regeneration by müller cells in adult mammalian retina. PLoS One, 5(8):e12425. doi: 10.1371/journal.pone.0012425.
  8. Balasubramanian, S., Babai, N., Chaudhuri, A., Qiu, F., Bhattacharya, S., Dave, B.J., Parameswaran, S., Carson, S.D., Thoreson, W.B., Sharp, J.G., Rao, M., Ahmad, I. (2009) Non cell-autonomous reprogramming of adult ocular progenitors: generation of pluripotent stem cells without exogenous transcription factors. Stem Cells. 27(12):3053-62. doi: 10.1002/stem.242.
  9. Yang, , Akhter., Chaudhuri, A.,  Kanmogne, G.D. (2009) HIV-1 gp120 induces cytokine expression, leukocyte adhesion, and transmigration across the blood-brain barrier: modulatory effects of STAT1 signaling. Microvasc. Res. 77(2):212-219. doi: 10.1016/j.mvr.2008.
  10. Chaudhuri, A., Yang. B., Gendelman, H.E., Persidsky, Y., Kanmogne, G.D. (2008) STAT1 signaling modulates HIV 1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. Blood, 111:2062-2072.
  11. Chaudhuri, A., Duan, F., Morsey, B., Persidsky, Y., Kanmogne, G.D. (2008) HIV-1 activates proinflammatory and interferon-inducible genes in human brain microvascular endothelial cells: putative mechanisms of blood-brain barrier dysfunction. J Cereb Blood Flow Metab. 28(4):697-711.
  12. Glanzer, J.G., Reynolds, A., Kadiu, I., Ricardo-Dukelow, M., Ciborowisky, P., Cerny, , Mosely, L., Chaudhuri, A., Thomas, M.P and Gendelman, H.W (2008) The synuclein activated microglial transcriptome, proteome and secretome: Functional profiling and links to the pathogenesis of Parkinson’s disease. J. Neurochem., 104: 1504-1525.
  13. Chaudhuri, A., Bowling, K., Funderburk, C., Imander, A and O’Donnell, J.M (2007) Interaction of genetic and environmental factors in a Drosophila Parkinsonism model. Neurosci. 27: 2457-2467.